WebJun 18, 2024 · Stains - Prostate specific membrane antigen (PSMA) In prostate carcinoma: PSMA's carboxypeptidase activity releases glutamate from vitamin B9 and other … WebNov 15, 2024 · Highlights. PSMA is a protein in prostate cells. Researchers have found that it helps fuel prostate cancer. This offers a new target for prostate cancer treatments. Prostate-specific antigen (PSA) can be an indicator of prostate cancer and is easily detected and measured with a blood test. But another protein, prostate-specific membrane antigen ...
PSMA: A New Target for Prostate Cancer Treatment
WebJan 23, 2024 · PSMA PET is a promising method for primary lymph node staging in prostate cancer. However, recent systematic reviews have identified only a limited number of studies with histopathology as a reference test. A systematic search was performed in PubMed and the Cochrane Library. An expedited systematic review was performed where we … WebNov 26, 2024 · The AAZTA chelator and in particular its bifunctional derivative AAZTA5 was recently investigated to demonstrate unique capabilities to complex diagnostic and therapeutic trivalent radiometals under mild conditions. This study presents a comparison of 68Ga, 44Sc and 177Lu-labeled AAZTA5-PSMA-617 with DOTA-PSMA-617 analogues. … the new inn malvern link
A prostate-specific membrane antigen (PSMA)-targeted …
WebSep 13, 2024 · Purpose In this retrospective study, we compared the diagnostic value of 68Gallium prostate-specific membrane antigen positron emission tomography computed tomography ([68Ga]PSMA PET/CT) in primary staging of patients with high-risk prostate cancer (PCa), in comparison to CT, magnetic resonance imaging (MRI), and bone scans, … WebJul 23, 2024 · Background The differential diagnosis between primary cholangiocarcinoma and metastatic pancreatobiliary adenocarcinoma is histologically challenging due to lack … WebAug 15, 2024 · We hypothesized that a hetero-bivalent agent targeting fibroblast activation protein alpha (FAP) and PSMA, as both are abundantly expressed within the TME, and the latter on prostate tumor cells, may enhance cancer detection and therapy. FAP is overexpressed on cancer-associated fibroblasts (CAFs) [ 6 ], while PSMA is expressed … the new inn moreleigh